OMICRON: RESEARCH & SCIENCE BACKED DATA 

SARS-CoV-2 variant B.1.1.529

covariant mutation source website
wikiepedia: SARS-CoV-2 Omicron variant

OMICRON MUTATIONS OF NOTE INCLUDE THE FOLLOWING:

  • Omicron has the N501Y spike mutation found in the alpha, beta and gamma variants, which enabled them to invade cells more successfully than the original virus. That mutation changed one amino acid — a building block of proteins — in the receptor-binding domain.
  • Omicron has a mutation in the Spike protein D614G that has rapidly surpassed others in prevalence. This mutation is in linkage disequilibrium with an ORF1b protein variant (P314L), making it difficult to discern the functional significance of the Spike D614G mutation from population genetics alone.
  • Omicron has the P681R mutation, which is a hallmark of the virological phenotype of the B.1.617.2/Delta variant and is associated with enhanced pathogenicity.
  • Omicron has the novel SARS-CoV-2 Spike mutation T478K, which is also located at the interface of the Spike/ACE2 interaction, and it is worryingly rising in prevalence among SARS-CoV-2 sequences collected since the beginning of 2021.
  • The Omicron variant has three mutations at the furin cleavage site. The furin cleavage site increases SARS-CoV-2 infectivity.
  • Omicron being “mild” does not necessarily mean its not deadly. The Delta variant was milder in its viral form, but allowed for the weakening of the immune system to the extent of leaving the organism open to fungal
    infections which were life-threatening.

RESEARCH BASED PAPERS INVOLVING OMICRON

The Omicron variant and potential predictions of secondary infections

READ PAPER

Global Omicron COVID cases rise as evidence for immune escape grows

READ PAPER

Threat Assessment Brief: Implications of the further emergence and spread of the SARS CoV 2 B.1.1.529 variant of concern (Omicron) for the EU/EEA first update

READ PAPER

Epidemiological Update
SARS-CoV-2 variants in the Region of the Americas

READ PAPER

OMICRON MUTATIONS.

Privacy Settings
We use cookies to enhance your experience while using our website. If you are using our Services via a browser you can restrict, block or remove cookies through your web browser settings. We also use content and scripts from third parties that may use tracking technologies. You can selectively provide your consent below to allow such third party embeds. For complete information about the cookies we use, data we collect and how we process them, please check our Privacy Policy
Youtube
Consent to display content from Youtube
Vimeo
Consent to display content from Vimeo
Google Maps
Consent to display content from Google